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10.1021/jf903116q J

rda: B

47 Studies in Diseased Participants The effect of hepatic impairment on oral semaglutide pharmacokinetics was studied in 56 patients with varying degrees of hepatic function categorized as having normal hepatic function, and mild, moderate and severe hepatic impairment received once-daily oral semaglutide (5 mg for 5 days followed by 10 mg for 5 days)

At 5mg: The first dose where GI effects become noticeable for many patients

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